serum adenosine deaminase activity and c-reactive protein levels in patients with brucellosis

Authors

alireza abdollahi

mehrnaz rasoulinejad

seyed jalil mousavi

fatemeh fattahi

akram sarbiaei

abstract

background and objective: brucellosis is a main transmittable zoonotic disease, which is endemic, and a common health burden in iran. adenosine deaminase (ada) is an essential enzyme which is involved in purine metabolism and its role in immune system is very important. the aim of this study was to determine serum changes of ada and c-reactive protein (crp) levels in patients with brucellosis.   patients and methods: the study was a case-control one on 36 patients and 36 controls. the serum level of ada and quantitative crp was measured in both patients and controls. we also measured the wright, coomb,s wright and 2-mecapto ethanol (2me) in two participants groups. statistical analysis was performed using spss for windows version 11.5 results: ada serum level in patients group showed a significant difference compared to control group (31.64±25.1 vs. 13.97±3.9, p

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Journal title:
iranian journal of pathology

Publisher: iranian society of pathology

ISSN 1735-5303

volume 4

issue 3 2009

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